Faculty Search Website  
 
News
Research
Faculty
Post Doctoral Personnel
Graduate Students
Seminars
Centers
Graduate Program
Shops
Administration Support
University of Pittsburgh
Health Sciences
School of Medicine
Home
Contact Us
CBP Faculty - Gerard L. Apodaca, Ph.D.

Gerard L. Apodaca, Ph.D.
Professor
Primary Appointment: Medicine, Renal-Electrolyte
Tel: 412-383-8893
Fax: 412-383-8955
gla6@pitt.edu
PubMed pub. listing
Apodaca Webpage
CBP Research Group(s):
CBMP Graduate Program Groups:
Membrane Traffic of Proteins and Lipids

Research Interest
Publications
  1. Apodaca, G., Kiss, S., Ruiz, W., Meyers, S., Zeidel, M., and Birder, L. Disruption of bladder epithelium barrier function after spinal cord injury. American Journal of Physiology. 284:F966-F976, 2003.
  2. Wang, E., Lee, J.-M., Johnson, J.P., Kleyman, T., Bridges, R., and Apodaca, G. Hydrostatic pressure-regulated ion transport in bladder uroepithelium. American Journal of Renal Physiology. 2003 Oct;285(4):F651-63. Epub 2003 May 27
  3. Wang, E., Truschel, S., and Apodaca, G. Analysis of hydrostatic pressure-induced changes in umbrella cell surface area. Methods. 30:207-217, 2003.
  4. Birder, L.A., Nakamura, Y., Kiss, S., Nealan, M.L., Barrick, S., Kanai, A.J., Wang, E., Ruiz, G., deGroat, W.C., Apodaca, G., Watkins, S., and Caterina, J. Altered bladder function in mice lacking the vanilloid receptor TRPV1. Nature Neuroscience, 5:856-860. 2002.
  5. Birder, LA., Nealen, M., Kiss, S., de Groat, W.C., Caterina, M.J., Wang, E., Apodaca, G., and Kanai, A.J. b-Adrenoceptor agonists stimulate endothelial nitric oxide synthase in rat urinary bladder urothelial cells. Journal of Neuroscience, 22:8063-8070, 2002.
  6. Kanai, A., Zeidel, M., Lavelle, J., Greenberger, J., Birder, L, DeGroat, W., Apodaca, G., Meyers, S., Ramage, R., Epperly, M. Manganese superoxide dismutase gene therapy protects against irradiation-induced cystitis. American Journal of Physiology, 283:F1304-1312. 2002.
  7. Lavelle, J., Meyers, S., Ramage, R., Bastacky, S., Doty, D., Apodaca, G., and Zeidel, M.L. Bladder permeability barrier: recovery from selective injury of surface epithelial cells. American Journal of Physiology, 283:F242-253, 2002.
  8. Magyar, C.E., White, K.E., Rojas, R., Apodaca, G., and Friedman, P.A. Expression of plasma membrane Ca2+-ATPase and NXC1 Na+/Ca2+ exchanger in distal convoluted tubule cells. American Journal of Physiology, 283:F29-F40, 2002.
  9. Truschel, S., Wang, E., Ruiz, W.G., Leung, S.-M., Rojas, R., Lavelle, J., Zeidel, M., Stoffer, D., and Apodaca, G. Stretch-regulated exocytosis/endocytosis in bladder umbrella cells. Molecular Biology of the Cell. 13:830-846, 2002.
  10. Liu, S.-H., Towler, M.C., Chen, E., Chen, C.-Y., Song, W., Apodaca, G. and Brodsky, F.M. A novel clathrin homologue that codistributes with cytoskeletal components functions in the trans-Golgi network. EMBO Journal. 20:272-284, 2001.
  11. Rajasekaran, S.A., Palmer, L.G., Moon, S.Y., Soler, A.P., Apodaca, G., Harper, J.F., Zheng, Y., and Rajasekaran, A.K. Na,K-ATPase activity is required for formation of tight junctions, desmosomes, and induction of polarity in epithelial cells. Molecular Biology of the Cell, 12:3717-3732, 2001.
  12. Rojas, R., W.G. Ruiz, S.-M. Leung, T.-S. Jou, and G. Apodaca. Cdc42-dependent modulation of tight junctions and membrane protein traffic in polarized MDCK epithelial cells. Molecular Biology of the Cell. 12:2257-2274, 2001.
  13. Altschuler, Y., Kinlough, C.L., Poland, P.A., Apodaca, G., Weisz, O.A. and Hughey, R.P. Clathrin-mediated endocytosis of MUC1 is regulated by glycosylation. Molecular Biology of the Cell. 11:819-831, 2000.
  14. Jou, T.-S., Leung, S.-M., Fong, L., Ruiz W., Nelson, J. and Apodaca, G. Selective alterations in biosynthetic and endocytic protein traffic in MDCK epithelial cells expressing mutants of the small GTPase Rac1. Molecular Biology of the Cell. 11:287-304, 2000.
  15. Lavelle, J.P., Meyers, S.A., Ruiz, W.G., Buffington, C.A.T., Zeidel, M.L. and Apodaca, G. Functional and structural urothelial derangements in feline interstitial cystitis: a human interstitial cystitis model. American Journal of Physiology. 278:F540-F553, 2000.
  16. Leung, S.-M., Ruiz, W.G. and Apodaca, G. Sorting of membrane and fluid at the apical pole of polarized MDCK cells. Molecular Biology of the Cell. 11:2131-2150, 2000.