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CBP Faculty - Meir Aridor, Ph.D.

Meir Aridor, Ph.D.
Associate Professor
Tel: 412-624-1970
Fax: 412-648-8330
aridor@pitt.edu
PubMed pub. listing
CBP Research Group(s):
Membrane Trafficking and Organelle Biogenesis
CBMP Graduate Program Groups:
Membrane Traffic of Proteins and Lipids

Research Interest


Publications
  1. Kimberly R. Long*, Yasunori Yamamoto*, Adam L. Baker, Simon C. Watkins, Carolyn B. Coyne, James F. Conway and Meir Aridor (2010) Sar1 Assembly Regulates Membrane Constriction and ER export. J. Cell Biol. 12;190(1):115-28.
  2. Béla Z. Schmidt, Rebecca J. Watts, Meir Aridor and Raymond A. Frizzell (2009). Cysteine String Protein promotes proteasomal degradation of CFTR by increasing its interaction with CHIP and promoting CFTR ubiquitylation. J. Biol. Chem. 13; 284(7): 4168-78.
  3. M. Aridor and K. N. Fish (2009) Selective Targeting of ER Exit Sites Supports Axon Development. Traffic 10 (11): 1669-84.
  4. Aridor M. (2007) Visiting the ER: The Endoplasmic Reticulum as a target for therapeutics in traffic related diseases. Advanced Drug Delivery Reviews 10;59(8):759-81.
  5. G. M. Mueller, O. B. Kashlan, J. B. Bruns, A. B. Maarouf, M. Aridor, T. R. Kleyman and R. P. Hughey (2007) Epithelial sodium channel exit from the endoplasmic reticulum is regulated by a signal within the carboxyl cytoplasmic domain of the a subunit J. Biol. Chem. In press.
  6. T. Iinuma, A. Shiga, K. Nakamoto, M. B. O?Brien, M. Aridor, N. Arimitsu, M. Tagaya, and K. Tani (2007) Mammalian Sec16/p250 plays a role in membrane traffic from the endoplasmic reticulum. J. Biol. Chem. 15;282(24):17632-9.
  7. A. Blumental-Perry, C.J. Haney, K.M. Weixel, S.C. Watkins, O.A. Weisz, and M. Aridor (2006). Phosphatidylinositol 4-Phosphate Formation at ER Exit Sites Regulates ER Export. Developmental Cell 11, 671-682
  8. Aridor M., Guzic, A.K., Bielli, A. and Kenneth N. Fish (2004) Endoplasmic Reticulum Export Site Formation and Function in Dendrites J. Neuroscience 24; 3770-3776
  9. Bielli A, C.J. Haney, G. Gabreski, S. C. Watkins, S. I. Bannykh and M. Aridor (2005) Regulation of Sar1 N-terminus by GTP Binding and Hydrolysis Promotes Membrane Deformation to Control COPII Vesicle Fission. J. Cell Biol. 171: 919-24.
  10. H. Zhang, B. Z. Schmidt, F. Sun, S. B. Condliffe, R.T. Youker, J. L. Brodsky, M. Aridor and R. A. Frizzell (2006) Cysteine String Protein monitors late steps in CFTR biogenesis J. Biol. Chem. 81: 11312-21.
  11. K. M. Weixel, A. Blumental-Perry, S. C. Watkins, M. Aridor, and O. A. Weisz, (2005) Distinct Golgi Populations of Phosphatidylinositol 4-Phosphate Regulated by Phosphatidylinositol 4-Kinases J. Biol. Chem 280(11):10501-8
  12. P. Pathre, K. Shome, A. Blumental-Perry, A. Bielli , C.J. Haney, S Alber, S. Watkins, G. Romero, and M. Aridor (2003) Activation of Phospholipase D by the Small GTPase Sar1 Is Required to support COPII Assembly and ER Export. EMBO J. 22: 4059-4069
  13. Romero G. Shome K. and Aridor M. (2005) Assay and measurment of PLD activation by Sar1 Method in Enzymology 404:108-15.
  14. W. Shimoi, I. Ezawa, K. Nakamoto, S. Uesaki, G. Gabreski, M. Aridor, Akitsugu Yamamoto, Masami Nagahama, Mitsuo Tagaya, and Katsuko Tani (2005) p125 Is Localized in Endoplasmic Reticulum Exit Sites and Involved in Their Organization J. Biol. Chem 18;280(11):10141-8