Wright, C. M., R. J. Chovatiya, N. E. Jameson, D. M. Turner, G. Zhu, S. Werner, D. M. Huryn, J. M. Pipas, B. W. Day, P. Wipf, and J. L. Brodsky. Pyrimidinone-Peptoid Hybrid Molecules with Distinct Effects on Molecular Chaperone Function and Cell Proliferation. Bioorg. Med. Chem. (2008) 16: 3291-3301
Tonsor, S. J., C. Scott, I. Boumaza, T. R. Liss, J. L. Brodsky, and E. Vierling. Heat shock protein 101 effects in A. thaliana: genetic variation, fitness, and phenotype under controlled temperate growth conditions. Molec. Ecol. (2008) 17: 1614-1626
Nakatsukasa, K., G. Huyer, S. Michaelis, and J. L. Brodsky. Dissecting the ER- associated degradation of a misfolded polytopic membrane protein. Cell (2008) 132: 101-112
Nakatsukasa, K. and J. L. Brodsky. Recognition and retro-translocation of misfolded proteins from the endoplasmic reticulum. Traffic (2008) 9: 861-870
Kang, Y., T. Talsone, C. C. Clement, S. W. Fewell, J. Aguirre, J. L. Brodsky, and G. Chiosis. Design of a fluorescent polarization assay platform for the study of human Hsp70. Bioorg. Med. Chem. Lett. (2008) 18: 3749-3751
Goeckeler, J. L., A, P. Petruso, J. Aguirre, C. C. Clement, G. Chiosis, and J. L. Brodsky. The yeast Hsp110, Sse1p, exhibits high affinity peptide binding. FEBS Lett. (2008) 582: 2393-2396
Hrizo, S. L., V. Gusarova, D. M. Habiel, J. L. Goeckeler, E. A. Fisher, and J. L. Brodsky. The Hsp110 Molecular Chaperone Stabilizes Apolipoprotein B from Endoplasmic Reticulum Associated Degradation (ERAD). J. Biol. Chem. (2007) 282: 32665-32675
Feng, D., Z. Xueqiang, C. Soromani, J. Toikkanen, K. Römisch, S. S. Vembar, J. L. Brodsky, S. Keränen, and J. Jäntti. The Trans-Membrane Domain is Sufficient for Sbh1p Function, its Association with the Sec61 Complex and Interaction with Rtn1p. J. Biol. Chem. (2007) 282: 30618-30628
Kashlan, O.B., G. M. Mueller, M. Z. Qamar, P. A. Poland, A. Ahner, R. C. Rubenstein, R. P. Hughey, J. L. Brodsky, and T. R. Kleyman. Small heat shock protein aA-crystallin regulates ENaC expression. J. Biol. Chem. (2007) 282: 28149-28156
Gusarova, V., J. Seo, M. L. Sullivan, S. C. Watkins, J. L. Brodsky, and E. A. Fisher. Golgi-associated maturation of very low density lipoproteins involves conformational changes of apolipoprotein B, but is not dependent on apolipoprotein E. J. Biol. Chem. (2007) 282:19453-19462
Scott, C. M., K. B. Kruse, B. Z. Schmidt, D. H. Perlmutter, A. A. McCracken, and J. L. Brodsky. ADD66, A Gene Required for the Endoplasmic Reticulum Associated Degradation (ERAD) of Alpha-1-Antitrypsin-Z in Yeast, Facilitates Proteasome Activity and Assembly. Mol. Biol. Cell (2007) 18: 3774-3787
Wahlman, J., G. N. DeMartino, W. R. Skach, N. J. Bulleid, J. L. Brodsky, and A. E. Johnson. Real-time fluorescence detection of ERAD substrate retro-translocation in a mammalian in vitro system. Cell (2007) 129: 943-955
Buck, T., C. M. Wright, and J. L. Brodsky. The activities and functions of molecular chaperones in the endoplasmic reticulum. Seminars Cell. Dev. Biol. (2007) 18: 751-761
Mandal, A., P. Lee, J. Chen, A. Heller, S. DiStasio, H. Oen, J. Victor, D. M. Nair, J. L. Brodsky and A. J. Caplan. Cdc37 has distinct roles in kinase biogenesis that affect synthesis and post-translational maturation. J. Cell Biol. (2007) 176: 319-328
Wright, C. M., S. W. Fewell, M. L. Sullivan, J. M. Pipas, S. C. Watkins, and J. L. Brodsky. The Hsp40 molecular chaperone, Ydj1p, along with the protein kinase C pathway, impact cell wall integrity in the yeast Saccharomyces cerevisiae. Genetics (2007) 175: 1649-1664
Rodina, A., M. Vilenchik, K. Moulick, J. Aguirre, J. Kim, A. Chiang, J. Litz, C. C. Clement, Y. Kang, Y. She, N. Wu, S. Felts, P. Wipf, J. Massague, X. Jiang, J. L. Brodsky, G. W. Krystal, and G. Chiosis. Selective chemical tools define Hsp90 as a major inhibitor of apoptosis in small cell lung cancer. Nature Chem. Biol. (2007) 3: 498-507
Brodsky, J. L. The protective and destructive roles played by molecular chaperones during endoplasmic reticulum associated degradation (ERAD). Biochem. J., (2007) 404: 353-363
Sparvero, L. J., S. Patz, J. L. Brodsky, and C. M. Coughlan. Proteomic analysis of the Amyloid Precursor Protein fragment C99: Expression in yeast. Analytic. Biochem. (2007) 370: 162-170
Jelenska, J., N. Yao, B. A. Vinatzer, C. M. Wright, J. L. Brodsky, J. T. Greenberg. A J- domain Virulence Effector of Pseudomonas syringae Remodels Host Chloroplasts and Suppresses Defenses. Curr. Biol. (2007) 17: 499-508
Ahner, A., K. Nakatsukasa, H. Zhang, R. A. Frizzell, and J. L. Brodsky. Small Heat Shock Proteins Select îF508-CFTR for ER Associated Degradation (ERAD). Mol. Biol. Cell (2007) 18: 806-814
