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CBP Faculty - Yang Hong, Ph.D.

Yang Hong, Ph.D.
Associate Professor
Tel: 412-648-2845
Fax: 412-648-8330
yhong@pitt.edu
PubMed pub. listing
CBP Research Group(s):
Cellular Organization and Cell-cell Communications
CBMP Graduate Program Groups:
Genomics, Proteomics and Metabolomics
Membrane Traffic of Proteins and Lipids

Research Interest
Publications
  1. Zhou W, Huang J, Watson AM, and Hong Y. (2012) W::Neo: a novel dual-selection marker for high efficiency gene targeting in Drosophila. PLoS ONE 7(2): e31997.
  2. Zhou W and Hong Y. (2012) Drosophila Patj plays a supporting role in apical-basal polarity but is essential for viability. Development 139(2):2891-6
  3. Huang J, Huang L, Chen Y, Austin E, Devor C, Roegiers F, and Hong Y. (2011) Differential regulation of adherens junction dynamics during apical-basal polarization. J. Cell Sci. 124(23):4001-3
  4. Huang J, Ghosh P, Hatfull GF, and Hong Y. (2011) Successive and targeted DNA integrations in Drosophila genome by Bxb1 and phiC31 integrases. Genetics 189(1):391-5
  5. Robinson BS, Huang J, Hong Y, and Moberg KH (2010) The apical membrane determinant Crumbs acts via the FERM-domain protein Expanded to regulate SWH signaling in Drosophila. Curr. Biol. 20(7):582-90
  6. Ling C, Zheng Y, Ying F, Yu J, Huang J, Hong Y, Wu S, Pan DJ. (2010) The apical transmembrane protein Crumbs functions as a tumor suppressor that regulates Hippo signaling through Expanded. Proc. Nat. Acad. Sci. 107(23):10532-7
  7. Huang J*, Zhou W*, Dong W, Watson AM, and Hong Y. (2009) Directed, efficient and versatile modifications of the Drosophila genome by genomic engineering. Proc. Nat. Acad. Sci. 106(20):8284-8289. (*:equal contribution) - Download PDF
  8. Huang J, Zhou W, Dong W, and Hong Y. (2009) Targeted engineering of the Drosophila genome. FLY (Austin) 3(4):274-277
  9. Huang J*, Zhou W*, Watson AM, Jan YN, and Hong Y. (2008) Efficient ends-out gene targeting in Drosophila. Genetics 180(1): 703-707. (*: equal contribution) - Download PDF
  10. Hristova M, Birse D, Hong Y, and Ambros V. (2005) The C. elegans heterochronic regulator LIN-14 is a novel transcription factor that controls the developmental timing of transcription from the insulin/IGF gene ins-33 by direct DNA binding. Mol. Cell Biol. 25(24):11059-11072
  11. Hong Y, Ackerman L, Jan LY, and Jan YN. (2003) Distinct roles of Bazooka and Stardust in the specification of Drosophila photoreceptor membrane architecture. Proc. Nat. Acad. Sci. 100(22):12712-12717
  12. Hong Y, Stronach B, Perrimon N, Jan LY, and Jan YN (2001) Drosophila Stardust interacts with Crumbs to control polarity of epithelia but not neuroblasts. Nature 414(6864):634-8
  13. Hong Y, Lee RC, and Ambros V. (2000) Structure and function analysis of LIN-14, a temporal regulator of postembryonic developmental events in C. elegans. Mol. Cell. Biol. 20(6):2285-95
  14. Hong Y*, Roy R*, and Ambros V. (1998) Developmental regulation of a cyclin-dependent kinase inhibitor controls postembryonic cell cycle progression in C. elegans. Development, 125(18): 3585-3597 (*: equal contribution)
  15. Hong Y., Lei H, Zhao YF, Han YM, and Shen TJ. (1994) Cloning, sequencing and expression of subtilisin Carlsberg gene from Baclillus licheniformins 2709. Chinese J. of Biotech. 10:24-33
  16. Hong Y. (1993) Construction of bacterial genomic DNA library using partial end-filling method. Prog. in Biochem. & Biophy. (Beijing, P.R.China) 20:205-210
  17. Lei H, Hong Y, and Shen TJ. (1993) PCR amplification and sequencing of the coding sequence of subtilisin Carlsberg from Baclillus licheniformins 2709. Chinese J. of Biochem. 9:411-418