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CBP Faculty - Guy Salama, Ph.D.

Guy Salama, Ph.D.
Professor
Primary Appointment: Cardiology
Tel: 412-648-9354
Fax: 412-648-8330
gsalama@pitt.edu
PubMed pub. listing
Salama Webpage
CBP Research Group(s):

CBMP Graduate Program Groups:
Cell Communication, Signaling and Ion Channel Biology

Research Interest


Publications
  1. Berkich D, Salama G, LaNoue KF. Mitochondrial membrane potentials in ischemic hearts Archives of Biochem & Biophys (in press)
  2. London L, Baker LC, Petkova-Kirova P, Nerbonne JM, Choi B-K, and Salama G. Dispersion of Repolarization and Refractoriness are Determinants of Arrhythmia Phenotype in Transgenic Mice with long QT J. Physiol. (London) 578: 115-129, 2007
  3. Mantravadi R, Gabris B, Liu T, Choi B-R, de Groat W, G. Ng A, and Salama G. Autonomic Nerve Stimulation reverses Ventricular Repolarization Sequence in Rabbit Hearts, Circulation Research, 100:72-80, 2007.
  4. Choi B-K, Liu T, and Salama G. Low Osmolarity Transforms Ventricular Fibrillation from complex to highly organized, with a dominant high frequency source, Heart Rhythm, 3(10): 1210-1220, 2006
  5. Choi B-R, Liu T, and Salama G. Calcium Transients influence Action Potential Amplitudes in Ventricular Fibrillation. IEEE Engineering in Medicine and Biology Society (EMBS): 12: 231-234, 2006
  6. Hwang S, Choi B-R, and Salama G. Monte Carlo Simulation of 3D Mapping of Cardiac Electrical Activity with Spinning Slit Confocal Optics. IEEE Engineering in Medicine and Biology Society (EMBS) 12: 184-188, 2006.
  7. Petkova-Kirova PS, Gursoy E, Mehdi H, London B and Salama G. Electrical Remodeling of Cardiac Myocytes from Mice with Heart Failure due to the over-expression of Tumor Necrosis Factor . Am J Physiol. Heart Circ Physiol. 290(5):H2098-107, 2006.
  8. Salama G, Arrhythmia Genesis: Aberrations of Voltage or Ca2+ Cycling? Heart Rhythm 31 (1):67-70, 2006.
  9. Tallini NY, Ohkura M, Choi B-R, Ji G, Imoto K, Doran R, Lee J, Plan P, Wilson J, Xin H.B, Robbins J, Salama G, Nakai J, and Kotlikoff MI, Imaging Cellular Signals in the Heart in Vivo: Cardiac Signaling Mice Expressing the High Signal Ca2+ Indicator GCaMP2 PNAS 103(12):4753-4758, 2006.
  10. Choi, B-R, Liu, T and Salama, G. Fiber Orientation Modulates Wave Kinetics in Ventricular Fibrillation J Cardiovascular Electrophysiology 14:851-860, 2003.
  11. Ivanova J, Salama G, Clancy RM, Schor NF, Nylander KD, Stoyanovsky DA. Formation of Nitroxyl and Hydroxyl Radical in Solution of sodium Trioxodinitrate: Effects of pH and Cytotoxicity J Biol Chem 2003 Aug 14
  12. Choi B-R, Burton F and Salama G. Cytosolic Ca2+ Triggers Early Afterdepolarizations and Torsade de Pointes in Rabbits with type 2 Long QT Syndrome. J Physiol. (London), 543.2: 615-631, 2002.
  13. Choi, B-R, Nho, W, Liu, T and Salama, G. Lifespan of Fibrillation Events, Circ Res 91:339-345, 2002.
  14. Drici, M-D, Baker, F, Plan, P, Barhanin, J, Romey, G, and Salama G. Mice Display Gender differences in Halothane-Induced Polymorphic Ventricular Tachycardia. Circulation 106:497-503, 2002.
  15. Baker LC, London B, Choi, B-R, Koren G, Salama G. Enhanced dispersion of repolarization and refractoriness in transgenic mouse hearts promotes reentrant ventricular tachycardia. Circulation Research 86:396-407, 2000.
  16. Choi B-R, and Salama G. Simultaneous maps of optical action potentials and Ca2+ transients in guinea pig hearts: mechanisms underlying concordant alternans. J Physiol (London) 529.1: 171-188, 2000.
  17. Choi B-R, and Salama G. Optical mapping of the rabbit atrio-ventricular node reveals discontinuities of propagation from atrial to nodal cells. Am. J. Physiol. 43(Heart Cir. Physiol 3):H829-H845; 1998.
  18. Stoyanovsky D, Murphy T, Anno PR, Kim Y-M, and Salama G. Nitric Oxide activates skeletal and cardiac ryanodine receptors. Cell Calcium 21: 19-29, 1997.
  19. Salama G, Efimov IR, and Kanai A. Subthreshold stimulation of the Purkinje system interrupts ventricular tachycardia as monitored with voltage-sensitive dyes and imaging techniques. Circ. Res. 74: 1-16, 1994.
  20. Blasdel G and Salama G. Voltage-sensitive dyes reveal a modular organization in monkey striate cortex. Nature 321: 579-585, 1986.
  21. Salama G, and Morad M. Merocyanine 540, as an optical probe of transmembrane electrical activity in the heart. Science 191:485-487, 1976.